金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Calcineurin A Aliases: CALNA; CNA1; PP2B; PP3CA; PPP2B; PPP3CA Entrez Gene IDs: 5530 (Human); 19055 (Mouse); 24674 (Rat) Background: Calcineurin A Calcineurin A, also known as PP2B and PPP3CA, is the 59 kDa catalytic subunit of the calcium/calmodulin-dependent protein phosphatase. When activated by calcium in the presence of the regulatory B subunit and calmodulin, Calcineurin A selectively removes phosphates from serine and threonine residues on target proteins. Although ubiquitously expressed, Calcineurin levels are highest in brain. Calcineurin function in brain is thought to play a role in the formation and retention of memories. Calcineurin activity is inhibited by the immunosuppressant drug Cyclosporine A bound to cyclophilins.