货号：ABE99

品牌：Merck Millipore

规格：

目录价：￥3608.00

市场价格：￥3066.80

会员价格：￥2886.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PRDM4 Antibody | ABE99 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes PRDM4 at the C2H2-type 4 region. View All» Molecular Weight: ~78 kDa observed View All» Epitope: C2H2-type 4 region View All» Immunogen: KLH-conjugated linear peptide corresponding to the C2H2-type 4 region of human PRDM4. View All» Background Information: PRDM4 (PFM1) is a member of the PR-domain family of proteins. Consistent with it functions as a transcription factor, this protein contains six C2H2-type zinc fingers and a SET domain. PRDM4 is found in the nucleus and is expressed in a variety of tissues. It is highly expressed in the pancreas, brain, ovaries, testis, and prostate. Data suggests that this protein plays a role in tumor suppression of ovarian, gastric and pancreatic tumors. PRDM4 is also linked to the NGF signal transduction pathway due to an increase in expression in cells treated with NGF. View All» Species Reactivity:

• Mouse

• Rat

• Pig

• Chimpanzee

• Rabbit

• Bovine

• Canine
  View All» Species Reactivity Note: Demonstrated to react with Mouse and Rat. Predicted to react with Porcine, Chimpanzee, Rabbit, Bovine, Canine, and Giant Panda based on 100% sequence homology. View All» Control: Mouse heart tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse heart tissue lysate.Western Blot Analysis: 0.05 µg/mL of this antibody detected PRDM4 on 10 µg of mouse heart tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9UKN5 View All» Entrez Gene Number: NP_036538 View All» Gene Symbol:
  • PRDM4

  • PFM1
    View All» Alternate Names:
    • PR domain zinc finger protein 4

    • PR domain-containing protein 4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: May function as a transcription factor involved in cell differentiation.SUBCELLULAR LOCATION: Nucleus Potential. TISSUE SPECIFICITY: Expressed in many tissues. Highly expressed in ovary, testis, pancreas, brain, heart and prostate.SEQUENCE SIMILARITIES: Contains 6 C2H2-type zinc fingers.Contains 1 SET domain. View All» Product Name: Anti-PRDM4 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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