货号：ABN111

品牌：Merck Millipore

规格：100Ug

目录价：￥5359.00

市场价格：￥4555.15

会员价格：￥4287.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RGS11 (C-terminus) Antibody | ABN111 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of RGS11. View All» Molecular Weight: ~53 kDa observed View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human RGS11. View All» Background Information: Regulator of G-protein signaling 11 (RGS11) is a multidomain GTPase containing one each of DEP, RGS, and G-protein gamma domains. Like other members of the R7 RGS family, RGS11 uses these domains to form multisubunit complexes, which process the light responses of retinal cells. RGS11 interacts with the RGS9 anchor protein (R9AP) and the 5 G-protein beta subunit (Gbeta5) to form a trimeric complex that regulates the activity of the metabotropic glutamate receptor 6 (mGluR6) in ON-bipolar cells. The RGS11 complex hydrolyzes GTP and inactivates the G-protein Galphao, which is activated by mGluR6 in dark environments. By this mechanism, the RGS11 complex accelerates the light response in ON-bipolar retinal cells. View All» Species Reactivity:

• Human

• Rat
  View All» Control: Human placenta tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human placenta tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected RGS11 in 10 µg of human placenta tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O94810 View All» Entrez Gene Number: NP_003825 View All» Gene Symbol: RGS11 View All» Alternate Names:
  • Regulator of G-protein signaling 11

  • RGS11
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-RGS11 (C-terminus) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rabbit View All»
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