货号：ABN165

品牌：Merck Millipore

规格：

目录价：￥4027.00

市场价格：￥3422.95

会员价格：￥3221.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MMEL1 Antibody | ABN165 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the lumenal topological domain of MMEL1. View All» Molecular Weight: ~90 kDa observed. Uniprot describes 3 isoforms produced by alternative splicing at ~89 kDa, ~69 kDa, and ~71 kDa. View All» Epitope: Lumenal topological domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the lumenal topological domain of human MMEL1. View All» Background Information: Membrane metallo-endopeptidase-like 1 (MMEL1) is a single-pass type II membrane protein belonging to the peptidase M13 family. MMEL1 plays an important role in pain perception, arterial pressure regulation, phosphate metabolism, and homeostasis. MMEL1 is predominantly expressed in testis and weakly expressed in brain, kidney and heart. Mutations of MMEL1 have been associated with primary biliary cirrhosis. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunohistochemistry Analysis: A 1:500-1,500 dilution from a representative lot detected MMEL1 in human testis and rat testis tissues. View All» Control: Mouse testis tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse testis tissue lysate.Western Blot Analysis: 1.0 µg/mL of this antibody detected MMEL1 in 10 µg of mouse testis tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q495T6 View All» Entrez Gene Number: NP_258428 View All» Gene Symbol:
  • MMEL1

  • MELL1

  • MMEL2

  • NEP2
    View All» Alternate Names:
    • Membrane metallo-endopeptidase-like 1

    • Membrane metallo-endopeptidase-like 2

    • NEP2(m)

    • Neprilysin II

    • NEPII

    • Neprilysin-2

    • NEP2

    • NL2

    • Membrane metallo-endopeptidase-like 1, soluble form

    • Neprilysin-2 secreted

    • NEP2(s)
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Western Blotting
        View All» Product Name: Anti-MMEL1 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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