货号:ABN175
品牌:Merck Millipore
规格:
目录价:¥4264.00
市场价格:¥3624.40
会员价格:¥3411.20
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Description:
Anti-LRRTM1
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Specificity:
This antibody recognizes the cytoplasmic domain of LRRTM1.
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Molecular Weight:
~59 kDa observed. An uncharacterized band may appear at ~18 kDa in some lysates.
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Epitope:
Cytoplasmic domain
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Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human LRRTM1.
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Background Information:
Leucine-rich repeat transmembrane neuronal protein 1 (LRRTM1) is a multidomain postsynaptic protein. It contains nine leucine-rich repeats, one LRRCT domain, and 1 LRRNT domain. The Leucine-rich repeat transmembrane neuronal proteins bind to presynaptic neurexins and promote cell adhesion. The Leucine-rich repeat transmembrane neuronal protein 1 is predominantly expressed in the forebrain and may play a role in differentiation and connectivity processes during the development of this region. The corresponding gene is imprinted in humans, and has been linked to neurodevelopmental disorders, such as schizophrenia. Mice deficient in LRRTM1 show cognitive deficits in various behavioral paradigms.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Canine, and Rhesus Macaque based on 100% sequence homology.
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Application Notes:
Western Blot Analysis: 2 µg/mL from a representative lot detected LRRTM1 in 10 µg of human fetal brain tissue lysate.
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Control:
Human salivary gland tissue lysate
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Quality Assurance:
Evaluated by Western Blot in human salivary gland tissue lysate.Western Blot Analysis: 2 µg/mL of this antibody detected LRRTM1 in 10 µg of human salivary gland tissue lysate.
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Purification Method:
Affinity purified
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Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
Q86UE6
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Entrez Gene Number:
NP_849161
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Gene Symbol:
LRRTM1
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Alternate Names:
Leucine-rich repeat transmembrane neuronal protein 1
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Product Name:
Anti-LRRTM1
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Concentration:
1.0 mg/mL
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
100 μg
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Format:
Affinity Purified
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Host:
Rabbit
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