货号：ABN283

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-FDPS View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~41 kDa observed. The calculated molecular weight is 48 kDa, however FDPS has been shown as a ~41 kDa band in western blots (Montalvetti, A., et al. (2003). Journal of Biological Chemistry. 278(19):17075-17083). View All» Immunogen: GST-tagged recombinant protein corresponding to human FDPS. View All» Background Information: Farnesyl pyrophosphate synthase, also known as FPPS and FDPS is a member of the FPP/GGPP synthase family and a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. View All» Control: Human cerebellum tissue lysate View All» Quality Assurance: Evaluated by Western Blotting in human cerebellum tissue lysate. Western Blotting Analysis: A 1:1,500 dilution of this antibody detected FDPS in 30 µg of human cerebellum tissue lysate. View All» Purification Method: Antigen Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: P14324 View All» Entrez Gene Number: 2224 View All» Gene Symbol: FDPS View All» Alternate Names:
  • (2E,6E)-farnesyl diphosphate synthase

  • Dimethylallyltranstransferase

  • Farnesyl diphosphate synthase

  • Geranyltranstransferase
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-FDPS View All» Concentration: 0.23 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 150 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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