货号：ABN286

品牌：Merck Millipore

规格：

目录价：￥4118.00

市场价格：￥3500.30

会员价格：￥3294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-FOXM1 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes three isoforms: FOXM1-pp (~95-110 kDa), FOXM1-B (isoform 2, ~83 kDa), and FOXM1A (isoform 4, ~90 kDa). View All» Molecular Weight: ~110 kDa observed View All» Immunogen: GST-tagged recombinant protein corresponding to human FOXM1. View All» Background Information: Forkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation and plays an important role in cell cycle progression by regulating both G1/S and G2/M phases. FOXM1 is also involved in DNA damage repair, angiogenesis, apoptosis, and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies. View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human and Rat. View All» Application Notes: Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FOXM1 in 10 µg of A431 cell lysate.Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected FOXM1 in rat testis tissue. View All» Control: Human testis tissue lysate View All» Quality Assurance: Evaluated by Western Blotting in human testis tissue lysate.Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FOXM1 in 10 µg of human testis tissue lysate. View All» Purification Method: Antigen Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q08050 View All» Gene Symbol:
  • FOXM1

  • FKHL16

  • HFH11

  • MPP2

  • WIN
    View All» Alternate Names:
    • Forkhead box protein M1

    • Forkhead-related protein FKHL16

    • Hepatocyte nuclear factor 3 forkhead homolog 11

    • HFH-11

    • HNF-3/fork-head homolog 11

    • M-phase phosphoprotein 2

    • MPM-2 reactive phosphoprotein 2

    • Transcription factor Trident

    • Winged-helix factor from INS-1 cells
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Product Name: Anti-FOXM1 View All» Concentration: 0.29 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 150 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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