货号：ABN41

品牌：Merck Millipore

规格：

目录价：￥4383.00

市场价格：￥3725.55

会员价格：￥3506.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-FGF9 Antibody | ABN41 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: UniProtKB/Swiss-Prot P31371 (FGF9_HUMAN) states a molecular weight of ~23 kDa. View All» Immunogen: KLH-conjugated linear peptide corresponding to human FGF9. View All» Background Information: Fibroblast growth factors are a family of intercellular signaling molecules that serve various roles in a number of different species. Most Fibroblast growth factors are exported from cells via a classical amino-terminal signal sequence that is cleaved from the mature protein during its passage through the secretory pathway. Like its other family members, Fibroblast growth factor-9 (FGF-9) is secreted from cells; however, it is different in that it does not contain a recognizable signal sequence. Also known as Glia-activating factor (GAF), FGF-9 is glycosylated, mildly hydrophobic, and secreted from glioma cells. It is suggested to play a critical role in myoblast migration, glial cell growth, glial differentiation, gliosis during repair and regeneration of brain tissue after damage, and in the survival of neuronal cells and glial tumors. Abnormal functioning of this molecule is associated with skeletal dysplasias, and autosomal dominant craniosynostosis syndromes. View All» Species Reactivity:

• Human

• Mouse

• Rhesus Macaque

• Bovine

• Pig

• Canine
  View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. Predicted to react with Rhesus Macaque, Bovine, Porcine, and Canine based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: 2 µg/mL of this antibody detected FGF9 in NIH/3T3 cells. View All» Control: Human cerebellum tissue lysate. View All» Quality Assurance: Evaluated by Immunohistochemistry in human cerebellum tissue.Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected FGF9 in human cerebellum tissue. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P31371 View All» Entrez Gene Number: NP_002001 View All» Gene Symbol: FGF9 View All» Alternate Names:
  • Glia-activating factor

  • GAF

  • Fibroblast growth factor 9

  • FGF-9

  • Heparin-binding growth factor 9

  • HBGF-9
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry (Paraffin)

    • Immunocytochemistry
      View All» Entrez Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. View All» UniProt Summary: FUNCTION: May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.SUBUNIT STRUCTURE: Monomer.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Glial cells. View All» Product Name: Anti-FGF9 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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