金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: COCO Aliases: Cerberus 2; Cerberus like-2; CKTSF1B3; DAND5; Dante; GREM3 Entrez Gene IDs: 199699 (Human); 23863 (Mouse); 685719 (Rat) Background: COCO COCO is a member of the DAN Domain family of BMP antagonists that includes DAN, Gremlin, PRDC, and Cerberus 1. DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. COCO binds and inhibits Xnr1, BMP-4, activin, and Wnt8. COCO may cooperate with Nodal in gastrulation and embryonic left-right axis formation