货号：ABN78

品牌：Merck Millipore

规格：100Ug

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-NeuN (rabbit) Antibody | ABN78 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes NeuN at the N-terminus. View All» Molecular Weight: ~46/48 kDa observed. An uncharacterized band appears at ~62 kDa in some lysates. View All» Epitope: N-terminus View All» Immunogen: GST-tagged recombinant protein corresponding to mouse NeuN. View All» Background Information: ABN78 is a rabbit polyclonal version of the Anti-NeuN, clone A60 (MAB377), a highly characterized and cited mouse monoclonal antibody that specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found. View All» Species Reactivity:

• Mouse

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Mouse, Human, and Rat. View All» Application Notes: Immunohistochemistry Analysis: 1:1,000 dilution from a representative lot detected NeuN in normal mouse hippocampus and normal mouse midbrain tissues.Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected NeuN in rat E18 cortex/hippocampus primary cultures. View All» Control: Mouse brain nuclear extract View All» Quality Assurance: Evaluated by Western Blot in mouse brain nuclear extract.Western Blot Analysis: 0.5 µg/mL of this antibody detected NeuN on 10 µg of mouse brain nuclear extract. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» Gene Symbol: NeuN View All» Alternate Names:
  • NEUronal Nuclei

  • clone A60

  • NeuN
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)

    • Immunocytochemistry
      View All» Product Name: Anti-NeuN (rabbit polyclonal) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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      © Merck Millipore代理ABN78 Anti-NeuN Antibody (rabbit);抗NeuN抗体（兔）store at +2℃ to +8℃，产品报价联系微信jinshanbio