金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SorCS3 Long Name: Sortilin-related VPS10 Domain Containing Receptor 3 Entrez Gene IDs: 22986 (Human); 66673 (Mouse); 294043 (Rat) Background: SorCS Family SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.