货号：ABN87

品牌：Merck Millipore

规格：100Ug

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DSCR3 Antibody | ABN87 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~39 kDa observed. An uncharacterized band may be observed at a molecular weight of ~160 kDa in some cell lysates. View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human DSCR3. View All» Background Information: Trisomy of human chromosome 21 result in patients with Down's syndrome, which is a complex developmental and neurodegenerative disease that is characterized with abnormal morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region. DSCR3 expresses Down syndrome critical region protein 3, which is reportedly expressed in many studied tissues. While it is suggested that this protein is involved in neuroexcitation and in cellular signaling, further study is still required to elucidate its role and mechanism of action. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Other homologies: Rat and Mouse (92% sequence homology). View All» Application Notes: Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected DSCR3 in human gastric tissue. View All» Control: A549 cell lysate View All» Quality Assurance: Evaluated by Western Blot in A549 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected DSCR3 in 10 µg of A549 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O14972 View All» Entrez Gene Number: NP_006043 View All» Gene Symbol:

• DSCR3

• DCRA

• DSCRA
  View All» Alternate Names:
  • Down syndrome critical region protein 3

  • Down syndrome critical region protein A
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. View All» UniProt Summary: TISSUE SPECIFICITY: Ubiquitously expressed View All» Product Name: Anti-DSCR3 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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