货号：ABN97

品牌：Merck Millipore

规格：

目录价：￥4383.00

市场价格：￥3725.55

会员价格：￥3506.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neurexin2 Antibody | ABN97 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~71 kDa observed. UniProtKB/Swiss-Prot Q9P2S2 (NRX2A_HUMAN) states 2 isoforms due to alternative promoter usage and alternative splicing at a molecular weight of ~185 kDa and ~177 kDa, with a beta isoform at a molecular weight of ~100 kDa. View All» Immunogen: KLH-conjugated linear peptide corresponding to human Neurexin-2. View All» Background Information: Neurexins are heavily glycosylated and processed neuronal transmembrane cell surface proteins likely involved in cell recognition and adhesion. (Missler, M., et al. (1998) 14(1):20-26.) Antibody Anti-neurexin 2 alpha (ABN97) was made against a peptide immunogen corresponding to a stretch of amino acids in the extracellular domain of human neurexin 2 alpha (Uniprot Q9P2S2). Although the theoretical full length of Neurexin 1alpha is 185 kDa, the protein detected in human, mouse and rat brain lysates shows a band around 70-80 kDa as a possible result of the posttranslational processing previously reported. The Immunohistochemical staining using ABN97 localizes this protein to neuronal cytoplasm also consistent with previous research. (Dean, C., et al., (2003). 6(7):708-716.) View All» Species Reactivity:

• Mouse

• Rat

• Human
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected Neurexin-2 in normal rat brain. View All» Control: PC12 tissue lysate. View All» Quality Assurance: Evaluated by Western Blot in PC12 tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Neurexin-2 in PC12 tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9P2S2 View All» Entrez Gene Number: NP_055895 View All» Gene Symbol:
  • NRXN2

  • KIAA0921
    View All» Alternate Names:
    • Neurexin-2-alpha

    • Neurexin II-alpha
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants. View All» UniProt Summary: FUNCTION: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.SUBUNIT STRUCTURE: The laminin G-like domain 1 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. Interacts with INADL.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. View All» Product Name: Anti-Neurexin2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-159424.htm
        © Merck Millipore代理ABN97 Anti-Neurexin2，产品报价联系微信jinshanbio