金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: LIR-6 Long Name: Leukocyte Immunoglobulin-like Receptor 6 Aliases: CD85i; LILRA1 Entrez Gene IDs: 11024 (Human) Background: LIR-6 Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged aa within the TM domain which interacts with FcRgamma. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.