货号：ABS196

品牌：Merck Millipore

规格：100Ug

目录价：￥3945.00

市场价格：￥3353.25

会员价格：￥3156.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Haptoglobin-Related Protein Antibody | ABS196 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the Peptidase S1 domain of Haptoglobin-related protein. View All» Molecular Weight: ~39 kDa observed. A band at a molecular weight of ~92 kDa due to dimerization may be observed in human serum (Smith, A.B., et al. (1995). Proc Natl Acad Sci USA. 92(22):10262-10266). View All» Epitope: Peptidase S1 domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the Peptidase S1 domain of human Haptoglobin-Related Protein. View All» Background Information: It is reported that trypanosome lytic factor (TRF) consists of a haptoglobin-related protein that serves as a toxic substance against trypanosomes. This constituent is a protein that is known to be a toxic subtype of HDLs. When bound to hemoglobin, it is shown to kill trypanosomes through its peroxidative activity. It is also suggested to serve as a biomarker for early stage Alzheimer's disease and may play a role in lipid metabolism and weight regulation. View All» Species Reactivity:

• Human

• Chimpanzee
  View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Chimpanzee based on 100% sequence homology. View All» Application Notes: Multiplex Assay Analysis: 100 ng/mL from a representative lot detected Haptoglobin-Related Protein. View All» Control: Human serum View All» Quality Assurance: Evaluated by Western Blot in human serum.Western Blot Analysis: 50 ng/mL of antibody detected Haptoglobin-Related Protein in 10 µg of human serum. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P00739 View All» Entrez Gene Number: NP_066275 View All» Gene Symbol: HPR View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in hepatoma G2 and leukemia molt-4 cell lines.SEQUENCE SIMILARITIES: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Contains 1 Sushi (CCP/SCR) domain.CAUTION: Although homologous to serine proteases, it has lost all essential catalytic residues and has no enzymatic activity. View All» Product Name: Anti-Haptoglobin-Related Protein View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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