货号：ABT113

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-LPA receptor 3 (Edg-7) Antibody | ABT113 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes LPA receptor 3 at the extracellular domain. View All» Molecular Weight: ~44 kDa observed View All» Epitope: Extracellular domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 3. View All» Background Information: Lysophosphatidic acid receptor 3 (LPA receptor 3), also known as Edg-7, is a G-protein coupled receptor that interacts with Gi and Gq proteins and activates the MAP kinase pathway. It is highly expressed in the prostate, pancreas, testes, heart, ovary, and lung. The LPA receptor mediates a number of cellular processes such as growth, apoptosis, cell migration, and cytoskeleton changes. View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human and Rat. Other homologies: Mouse (83% sequence homology). View All» Application Notes: Immunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected LPA receptor 3 in human prostatic glandular epithelium tissue. View All» Control: Pc3 Cell Lysate View All» Quality Assurance: Evaluated by Western Blot in PC3 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected LPA receptor 3 on 10 µg of PC3 cell lysate. Western Blot performed without Tween View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Uby5 View All» Entrez Gene Number: Np_036284 View All» Gene Symbol:
  • Lpar3

  • Edg7

  • Lpa3
    View All» Alternate Names:
    • Lysophosphatidic Acid Receptor 3

    • Lpa Receptor 3

    • Lpa-3

    • Lysophosphatidic Acid Receptor Edg-7
      View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» Entrez Gene Summary: This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008]. View All» UniProt Summary: FUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.SEQUENCE SIMLARITIES: Belongs to the G-protein coupled receptor 1 family. View All» Product Name: Anti-LPA receptor 3 (Edg-7) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-159636.htm
        © Merck Millipore代理ABT113 Anti-LPA receptor 3 (Edg-7)，产品报价联系微信jinshanbio