货号：ABT117

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Alpha-(1,3)-fucosyltransferase 7 Antibody | ABT117 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Alpha-(1,3)-fucosyltransferase 7 at the lumenal domain. View All» Molecular Weight: ~52 kDa observed. The calculated molecular weight of this protein is 39 kDa, but can be observed at ~52-55 kDa due to high glycosylation. (Bengtson, P., et al. (2001). The Journal of Biological Chemistry. 276(34):31575–31582.) View All» Epitope: Lumenal domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the lumenal domain of human Alpha-(1,3)-fucosyltransferase 7. View All» Background Information: The alpha-(1,3)-fucosyltransferase 7 (Fuc-TVII) protein is a member of the glycosyltransferase 10 family. It is expressed in leukocytes. The precise role of alpha-(1,3)-fucosyltransferase 7 has not been fully deciphered; however, previous studies have suggested that it is involved in glycosylation pathway leading to the production of fucosylated glycans and sialyl Lewis x ligands which mediate the interaction of selectins and leucocytes, in which selectins mediate the adhesion of leucocytes to platelets or targeted endothelial cells. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Control: Human placenta tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human placenta tissue lysate.Western Blot Analysis: 0.25 µg/mL of this antibody detected Alpha-(1,3)-fucosyltransferase 7 on 10 µg of human placenta tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified Rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q11130 View All» Entrez Gene Number: NP_004470 View All» Gene Symbol: FUT7 View All» Alternate Names:
  • Alpha-(1,3)-fucosyltransferase

  • Fucosyltransferase 7

  • Fucosyltransferase VII

  • Fuc-TVII

  • FucT-VII

  • Galactoside 3-L-fucosyltransferase

  • Selectin ligand synthase
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. [provided by RefSeq, Jul 2008]. View All» UniProt Summary: FUNCTION: May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens.CATALYTIC ACTIVITY: GDP-L-fucose + alpha-2,3-Neu-N-acetyl-1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R = GDP + alpha-2,3-Neu-N-acetyl-1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl-R.PATHWAY: Protein modification; protein glycosylation.SUBCELLULAR LOCATION: Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein. Note: Membrane-bound form in trans cisternae of Golgi.TISSUE SPECIFICITY: Leukocytic/myeloid lineage cells.SEQUENCE SIMILARITIES: Belongs to the glycosyltransferase 10 family. View All» Product Name: Anti-Alpha-(1,3)-fucosyltransferase 7 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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