货号：ABT129

品牌：Merck Millipore

规格：100Ug

目录价：￥5359.00

市场价格：￥4555.15

会员价格：￥4287.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Calponin-1 Antibody | ABT129 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of Calponin-1. View All» Molecular Weight: ~33 kDa observed View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human Calponin-1. View All» Background Information: Calponin 1 is a 34 kDa protein that is predominantly found in smooth muscle tissue. It is a high-affinity actin-binding protein, but also interacts with tropomyosin, and calmodulin to modulate muscle contraction. When bound to F-actin, it inhibits the activity of the actin-activated myosin ATPase. Calponin 1 is regulated by reversible phosphorylation involving PKC and CAMKII kinases, and type 2A phosphatases. In non-muscle cells, calponin 1 may play a role in cell migration, motility, and proliferation. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Bovine, Chimpanzee, and Sheep based on 100% sequence homology. Other homologies: Rat (92% sequence homology) and Mouse (83% sequence homology). View All» Application Notes: Immunohistochemistry Analysis: A 1:1,000 dilution from a reprsesentative lot detected Calponin-1 in human seminal vesicle tissue.Immunofluorescence Analysis: A 1:500 dilution from a representative lot detected Calponin-1 in smooth muscle cells from human seminal vesicle tissue. View All» Control: Human aortic smooth muscle tissue View All» Quality Assurance: Evaluated by Western Blot in human aortic smooth muscle tissue.Western Blot Analysis: 0.1 µg/mL of this antibody detected Calponin-1 in human aortic smooth muscle tissue. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P51911 View All» Entrez Gene Number: NP_001290 View All» Gene Symbol: CNN1 View All» Alternate Names:

• Calponin-1

• Basic calponin, Calponin H1, smooth muscle
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunohistochemistry (Paraffin)

  • Immunofluorescence
    View All» Product Name: Anti-Calponin-1 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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