货号：ABT290

品牌：Merck Millipore

规格：

目录价：￥3978.00

市场价格：￥3381.30

会员价格：￥3182.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DSG2 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~145 kDa observed. An uncharacterized band may appear at ~40 kDa in some lysates. View All» Immunogen: GST-tagged recombinant protein corresponding to human DSG2. View All» Background Information: Desmoglein-2 (DSG2) is a single-pass type I membrane protein. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmosomal cadherins, consisting of four desmogleins (DSG1-4) and three desmocollins (DSC1-3) in humans, mediate adhesion through calcium-dependent homophilic/heterophilic interactions. DSG2 is widely expressed in epithelial and non-epithelial tissues such as the intestine, epidermis, testis, and heart. Mutations in DSG2 have been assoicated with familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10) and cardiomyopathy dilated type 1BB (CMD1BB). View All» Species Reactivity: Human View All» Control: HepG2 cell lysate View All» Quality Assurance: Evaluated by Western Blotting in HepG2 cell lysate.Western Blotting Analysis: A 1:2,000 dilution of this antibody detected DSG2 in 30 µg of HepG2 cell lysate. View All» Purification Method: Antigen Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q14126 View All» Gene Symbol:

• DSG2

• CDHF5
  View All» Alternate Names:
  • Desmoglein-2

  • Cadherin family member 5

  • HDGC
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-DSG2 View All» Concentration: 0.23 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 150 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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