货号：ABT35

品牌：Merck Millipore

规格：

目录价：￥3978.00

市场价格：￥3381.30

会员价格：￥3182.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-pan-Cadherin Antibody | ABT35 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody has been shown to react with VE, E, N, and K- Cadherins. It is predicted to also react with P and R Cadherins. View All» Molecular Weight: ~120-130 kDa observed. This antibody has been shown to react with VE, E, N, and K- Cadherins. It is predicted to also react with P and R Cadherins. View All» Immunogen: KLH-conjugated linear peptide corresponding to amino acid sequence common to human VE, E, N, K, P, and R Cadherins. View All» Background Information: Cadherins are a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell adhesion, which play important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. The members of the family are differentially expressed in various tissues and function in the maintenance of tissue integrity, morphogenesis, and migration. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin), neural cadherin (N-cadherin), placental cadherin (P-cadherin) and retinal cadherin (R-cadherin). Type II include kidney cadherin (K-cadherin) and osteoblast cadherin (OB-cadherin). Classical cadherins, which include N-cadherin and E-cadherin, feature a 24-amino acid sequence in the carboxy terminal which is conserved among cadherin family proteins and across animal species; antibodies generated against this sequence are thus termed “pan-cadherin” antibodies, as they detect cadherin proteins in a variety of samples. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Monkey
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, Rat, and Monkey. View All» Control: A431, C2C12, Huvec, NIH/3T3, C6, and Cos-1 cell lysates View All» Quality Assurance: Evaluated by Western Blot in A431, C2C12, Huvec, NIH/3T3, C6, and Cos-1 cell lysates.Western Blot Analysis: 1 µg/mL of this antibody detected pan-Cadherin on 10 µg of A431, C2C12, Huvec, NIH/3T3, C6, and Cos-1 cell lysates. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» Gene Symbol:
  • CDH1

  • CDHE

  • UVO
    View All» Alternate Names:
    • Cadherin-1

    • CAM 120/80

    • Epithelial cadherin

    • E-cadherin

    • Uvomorulin

    • CD324

    • E-Cad/CTF1

    • E-Cad/CTF2

    • E-Cad/CTF3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-pan-Cadherin View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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