货号：ABT37

品牌：Merck Millipore

规格：

目录价：￥4146.00

市场价格：￥3524.10

会员价格：￥3316.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Fas-binding factor 1 (Albatross) Antibody | ABT37 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~130 kDa observed. Other isoforms may be detected in some lysates with calculated molecular weights at 69 kDa & 98 kDa. View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human Fas-binding factor 1 (Albatross). View All» Background Information: Fas-binding factor 1 (protein Albatross) is a keratin-binding protein that is important for cellular stability. Albatross combines with Par3 to control the structure of the apical junction complex. Loss of albatross expression has been linked to a weakening in cell-cell adhesion and a propensity for the existance of single cells. Albatross, in addition to other keratin binding proteins, may be involved in the polarization of epithelial cells. View All» Species Reactivity:

• Human

• Mouse

• Chimpanzee

• Rhesus Macaque
  View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. Predicted to react with Chimpanzee and Rhesus Macaque based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Fas-binding factor 1 (Albatross) in NIH/3T3 and HeLa cells. View All» Control: CACO-2 cell lysate View All» Quality Assurance: Evaluated by Western Blot in CACO-2 cell lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected Fas-binding factor 1 (Albatross) in 10 µg of CACO-2 cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8TES7 View All» Entrez Gene Number: NP_001074011 View All» Gene Symbol:
  • FBF1

  • ALB
    View All» Alternate Names:
    • Fas-binding factor 1

    • FBF-1

    • Protein albatross
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3.SUBUNIT STRUCTURE: May interact with FAS cytoplasmic domain (By similarity). Interacts with PARD3.SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton › centrosome › centriole. Cytoplasm › cytoskeleton › spindle pole. Cell junction. Note: Associates with the mother centriole. Localizes to the apical junction complex (AJC) in epithelial cells.TISSUE SPECIFICITY: Present in various epithelial cells (at protein level).SEQUENCE CAUTION: The sequence BAB71400.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAB84871.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. View All» Product Name: Anti-Fas-binding factor 1 (Albatross) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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