金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Ras Long Name: v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Jomolog Aliases: c-K-ras; Ki-Ras; KRAS; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; Oncogene Ras; RASK2 Entrez Gene IDs: 3845 (Human); 16653 (Mouse); 24525 (Rat) Background: Ras The Ras proteins (H-Ras, N-Ras, and two splice variants of K-Ras) define a closely related family of 21 kDa GTPases that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. Receptor tyrosine kinases and G-protein coupled receptors activate Ras, and effectors include Raf and PI 3-kinase. Activating mutations of Ras, which impair GTPase activity and stabilize the active state, are found in nearly one-third of all human cancers.