货号：ABT97

品牌：Merck Millipore

规格：

目录价：￥4146.00

市场价格：￥3524.10

会员价格：￥3316.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-KIF3B View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~85 kDa observed View All» Epitope: . View All» Immunogen: KLH-conjugated linear peptide corresponding to human KIF3B. View All» Background Information: Kinesin-like protein KIF3B (KIF3B) tethers chromosomes to the spindle pole and is involved in chromosomal movement. It forms a heterotrimeric protein with KIF3A and kinesin-like associated protein (KAP3). Both KIF3A and KIF3B contain an N-terminal globular motor domain, a potential neck coiled-coil region, a highly charged hinge region, a coiled-coil stalk region, and a C-terminal tail (The C-terminus region binds to KAP3). KIF3B interacts directly with certain proteins, such as CLC-5, IFT20, and the SMC3 subunit of the cohesion complex. It was shown to facilitate CLC-5 plasma membrane expression, endocytosis and microtubular transport in patients with Dent’s disease. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Chicken, Bovine, Xenopus, Rat, Rhesus Macaque, and Mouse based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected KIF3B during telophase in A431 cells and during cytokinesis in HeLa cells. Punctate cytoplasmic staining has been observed in KIF3B-GFP transfected HEK293 cells (Reed, A. A., et al. (2010). Am J Physiol Renal Physiol. 298(2):F365-380.). View All» Control: Human testis tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human testis tissue lysate.Western Blot Analysis: 5 µg/mL of this antibody detected KIF3B in 10 µg of human testis tissue lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O15066 View All» Entrez Gene Number: NP_004789 View All» Gene Symbol: KIF3B View All» Alternate Names:

• Kinesin-like protein KIF3B

• HH0048

• Microtubule plus end-directed kinesin motor 3B
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry
    View All» Product Name: Anti-KIF3B View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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