货号：AG208

品牌：Merck Millipore

规格：100Ug

目录价：￥2917.00

市场价格：￥2479.45

会员价格：￥2333.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Vesicular Glutamate Transporter 1, control peptide for AB5905 View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: Synthetic peptide from rat VGLUT1 protein. View All» Background Information: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate. View All» Key Applications: Cell Function Assay View All» Application Notes: For use in blocking the reactivity of AB5905. Optimal working dilution must be determined by the end user. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: a Na(+)-dependent inorganic phosphate cotransporter. View All» UniProt Summary: FUNCTION: SwissProt: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. SIZE: 560 amino acids; 61665 Da [MW of unprocessed precursor] SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in the cerebellum, cerberal cortex and hippocampus. Isoform 2 is expressed specifically in retina.SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. View All» Species: Rat View All» Brand Family: Chemicon View All» Presentation: Liquid. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 3 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Gene Symbol:

• VGluT1

• Solute carrier family 17 member 7

• Brain-specific Na(+)-dependent inorganic phosphate cotransporter

• Slc17a7

• Bnpi
  View All» Product Name: Vesicular Glutamate Transporter 1, control peptide for AB5905 View All» Alternate Names: VGLUT1; BNPI View All» Concentration: 1 mg/mL View All» UniProt Number: Q62634 View All» Entrez Gene Number: NP_446311 View All»
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