货号:AG253
品牌:Merck Millipore
规格:
目录价:¥2951.00
市场价格:¥2508.35
会员价格:¥2360.80
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Description:
Heme Oxygenase 1, control peptide for AB1284
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Trade Name:
Chemicon (Millipore)
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Qty/Pk:
100 µg
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Product Overview:
Synthetic peptide corresponding to amino acid residues [12-25]+Cys-NH2 of human heme oxygenase-1. Sequence: H-D-L-S-E-A-L-K-E-A-T-K-E-V-H-C-NH2. This sequence is totally conserved in HO-1 from pig, rat and mouse. MOLECULAR WEIGHT: 1671.9
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Key Applications:
Peptide Inhibition Assay
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Application Notes:
Antibody blocking (AB1284) Optimal working dilution must be determined by the end user.
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
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UniProt Summary:
FUNCTION: SwissProt: P09601 # Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.SIZE: 288 amino acids; 32819 Da SUBCELLULAR LOCATION: Microsome.SIMILARITY: SwissProt: P09601 ## Belongs to the heme oxygenase family.
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Species:
Rat
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Brand Family:
Chemicon
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Presentation:
White lyophilized powder. Soluble in water.
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UniProt Number:
P09601
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Storage Conditions:
Long term storage at -20°C in a sealed container with desiccant.
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Gene Symbol:
-
HMOX1
-
HO
-
HO-1
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OTTHUMP00000028925
-
bK286B10
-
HO1
-
EC 1.14.99.3
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Product Name:
Heme Oxygenase 1, control peptide for AB1284
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Entrez Gene Number:
NM_002133.1
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Purity:
88% by HPLC
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