货号：AG340

品牌：Merck Millipore

规格：

目录价：￥2564.00

市场价格：￥2179.40

会员价格：￥2051.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Epithelial Sodium Channel γ, control peptide for AB3534P View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: ENACgamma (Epithelial Sodium Channel gamma) control peptide for use with Catalog Number AB3534P. A 14 amino acid peptide sequence near the N-terminus of rat ENaC gamma. View All» Key Applications: Cell Function Assay View All» Application Notes: Antibody blocking (AB3534P) ELISA Optimal working dilution must be determined by the end user. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: P51170 # Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.SIZE: 649 amino acids; 74270 Da SUBUNIT: Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.PTM: Phosphorylated on serine and threonine residues (By similarity). & Ubiquitinated; this targets individual subunits for endocytosis and proteasome-mediated degradation (By similarity).DISEASE: SwissProt: P51170 # Defects in SCNN1G are a cause of Liddle syndrome [MIM:177200]. It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel.SIMILARITY: SwissProt: P51170 ## Belongs to the amiloride-sensitive sodium channel family. View All» Species: Rat View All» Brand Family: Chemicon View All» Presentation: Liquid in PBS pH 7.4, containing 0.1% sodium azide. View All» Storage Conditions: Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Gene Symbol:

• SCNN1G

• SCNEG

• Gamma-ENaC

• ENaCg

• Gamma-NaCH

• ENaCgamma

• PHA1
  View All» Product Name: Epithelial Sodium Channel γ, control peptide for AB3534P View All» Alternate Names: ENaC gamma View All» Concentration: 1 mg/mL View All» UniProt Number: P51170 View All» Entrez Gene Number: NM_001039.3 View All»
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