货号：AG659

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: VEGF Receptor-3, control peptide for AB3127 View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: Control peptide for Chemicon Cat. No. AB3127 (Rabbit anti-mouse FLT-4). Peptide corresponds to a 20 amino acid sequence within the cytoplasmic, c-terminus of mouse FLT-4. FLT-4, also known as VEGF receptor 3 (VEGFR3), is a receptor tyrosine kinase that is the receptor for VEGF-C. View All» Key Applications: Peptide Inhibition Assay View All» Application Notes: Antibody blocking to confirm specificity (use 5-10ug peptide per 1ug antibody) ELISA Control peptide, because of it's small size (2-3 kDa), is not recommended for Western. Optimal working dilutions must be determined by end user. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: P35916 # Receptor for VEGFC. Has a tyrosine-protein kinase activity.SIZE: 1298 amino acids; 145599 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.TISSUE SPECIFICITY: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.DISEASE: SwissProt: P35916 # Defects in FLT4 are the cause of hereditary lymphedema I [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment. Hereditary lymphedema I shows autosomal dominant inheritance and is characterized by onset usually at birth. & Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10/% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.SIMILARITY: SwissProt: P35916 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain. View All» Species: Mouse View All» Brand Family: Chemicon View All» Storage Conditions: Store at -20ºC or below in undiluted aliquots. For short-term use, unopened, undiluted vials may be stored at 2-8ºC for less than a week. Avoid repeated freeze-thaw cycles. View All» Gene Symbol:

• FLT4

• PCL

• VEGFR-3

• FLT41

• VEGFR3

• EC 2.7.10.1
  View All» Product Name: VEGF Receptor-3, control peptide for AB3127 View All» Alternate Names: FLT-4 View All» UniProt Number: P35916 View All» Entrez Gene Number:
  • NM_002020.3

  • NM_182925.3
    View All»
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