R&D Systems代理MAB3716 Human/Mouse PLC-gamma 2 MAb (Clone 346404) (100 UG)

2025-06-28

货号:MAB3716

品牌:R&D Systems

规格:100ug

目录价:¥3870.00

市场价格:¥3096.00

会员价格:¥3096.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Molecule Information: PLC-gamma 2 Long Name: Phospholipase C gamma 2 Aliases: PLCG2 Entrez Gene IDs: 5336 (Human); 234779 (Mouse); 29337 (Rat) Background: PLC-gamma 2

    View PLC gamma 2 IHC images. The Phospholipase C family consists of 13 isozymes within six subfamilies, PLC-beta, -gamma, -delta, -epsilon, -zeta, and -eta. PLC-gamma 2 (Phospholipase C gamma-2) contains two SH2 and 1 SH3 domains and is primarily limited to cells of hematopoietic lineage. PLC-gamma 2 is activated by receptor tyrosine kinases in response to growth factors, neurotransmitters, and hormones. Activated PLC-gamma 2 catalyzes the hydrolysis of phosphatidylinositol 4, 5-biphosphate to produce the second messengers inositol 1, 4, 5-triphosphate (IP3) and diacylglycerol (DAG). IP3 mobilizes the release of calcium while DAG activates protein kinase C. PLC-gamma 2 is involved in collagen induced signaling in platelets and antigen-dependent signaling in B-lymphocytes.

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