货号：AG796

品牌：Merck Millipore

规格：

目录价：￥4739.00

市场价格：￥4028.15

会员价格：￥3791.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Angiotensin Converting Enzyme, bovine View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 1 units View All» Product Overview: ACE (kininase II, EC 3.4.15.1) is a zinc dipeptidyl carboxypeptidase (Kozlowski et al., 1992). ACE catalyses both angiotensin I transformation to angiotensis II (a potent vasopressor agent) and degradation of bradikinin, a vasodepressor. Thus, ACE appears to play a key role in regulating vascular tone and remodeling as well as in the development of atherosclerotic lesions. Increasing evidence asuggests that ACE plays an important role in vascular pathology. Recent studies show two new functions for this important enzyme: 1) ACE enhances presentation of endogenous antigens (such as HIV gp160-derived peptide p18) to MHC class I-restricted T-lymphocytes (Kozlowski et al., 1992); 2) amino-terminal domain of ACE efficiently cleaves hemoregulatory tetrapeptide N-Ac-Ser-Asp-Lys-Pro (Reiger et al., 1993; Rousseau et al., 1995) which is involved in the control of haemopoetic stem cell proliferation (the amount of this peptide greatly decreases in patients undergoing cancer chemotherapy) (Bogden, 1991). View All» Key Applications: Positive Control View All» Application Notes: 1) As a reference in SDS-PAGE and Western blotting in combination with anti-ACE MABs (MAB3500 and MAB3502). For Western with anti-ACE monoclonal antibodies load 20 ng/lane. 2) As a reference antigen for immunoprecipitation of ACE from various tissue samples. 3) For enzymatic studies (substrate specificity, enzyme kinetics, etc.). Optimal working concentrations must be determined by the end user. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Bovine View All» Molecular Weight: 170 kDa under reducing and non-reducing conditions. View All» Brand Family: Chemicon View All» Source: Isolated from bovine lung membrane by lisinopril-affinity chromatography (ref 5). View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Maintain at 4°C for up to one month. A decrease in activity may occur within prolonged storage at 4°C. View All» Gene Symbol:

• ACE

• DCP1
  View All» Product Name: Angiotensin Converting Enzyme, bovine View All» Alternate Names: ACE; CD143; DCP1; Peptidyl-dipeptidase A; Peptidase P View All» Concentration: See lot specific Datasheet for specific concentration and activity. View All» UniProt Number: P12820 View All» Specific Activity: One unit produces 1 mmole of hippuric acid or His-Leu from Hippuril-His-Leu per min in 0.1 M phosphate buffer-300 mM NaCl, pH 8.3 at 37&deg:C. pH-OPTIMUM: pH 7.5-8.5 View All» Purity: >95% as determined by SDS-PAGE. View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：https://www.16ao.com/thread-160109.htm
  © Merck Millipore代理AG796 ANGIOTENSIN CONVERT ENZ(BOV)-1.5U，产品报价联系微信jinshanbio