金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: G-CSF R/CD114 Long Name: Granulocyte Colony Stimulating Factor Receptor Aliases: CD114; CSF3R; Csfgr Entrez Gene IDs: 1441 (Human); 12986 (Mouse) Background: G-CSF Receptor Human G-CSF R is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSF R exist that differ in their transmembrane C-terminal region. Human and mouse G-CSF R are 64% identical at the aa level. G-CSF R is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.