货号：ALP20

品牌：Merck Millipore

规格：1EA

目录价：￥5125.68

市场价格：￥4356.83

会员价格：￥4100.54

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Apolipoprotein A-II, human View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 500 µg View All» Product Overview: High Density Lipoprotein (HDL) isolated by sequential isopycnic ultracentrifugation are delipidated. Apo A-II is purified by column chromatography in 6M urea (Schonfeld et al. 1977). Purity is determined by quantitative densitometry of SDS polyacrylamide gels (Laemlli 1970). Protein is determined by the Pierce BCA method (which was found to be comparable to the Lowry method) with 1% BSA as the standard. Apo A-II, which is a dimer composed of identical subunits, has a Mr of 17 kD and a pI of 4.9. Apo-II activates hepatic lipase and inhibits LCAT. Apolipoproteins are soluble in aqueous solutions. However, due to its amphipathic structure Apo-II self-associates into oligomers at high protein concentrations. Apo A-II exists as dimers in buffers with 5M guanidine-HCL or 6M urea. MOLECULAR WEIGHT: 17,400 View All» Key Applications: Positive Control View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. View All» UniProt Summary: FUNCTION: SwissProt: P02652 # May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.SIZE: 100 amino acids; 11175 Da SUBUNIT: Homodimer; disulfide-linked. Also forms a disulfide- linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Plasma; synthesized in the liver and intestine.SIMILARITY: SwissProt: P02652 ## Belongs to the apolipoprotein A2 family. View All» Species: Human View All» Brand Family: Chemicon View All» Source: Normal human plasma, fresh, non-frozen. Tested negative for HIV-1, HIV-2, HCV and HBc antibodies and HBsAg. View All» Presentation: Liquid in 10 mM NH4HCO3, pH 7.4. Non-sterile, no preservatives. View All» UniProt Number: P02652 View All» Storage Conditions: Maintain lyophilized material at View All» Gene Symbol:

• APOA2

• ApoA-II

• Apo-AII
  View All» Product Name: Apolipoprotein A-II, human View All» Entrez Gene Number: NM_001643.1 View All» Alternate Names: ApoAII View All» Concentration: 4.89 mg/mL View All» Purity: > 98% View All»
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