货号：ALP60-100UG

品牌：Merck Millipore

规格：1EA

目录价：￥2348.14

市场价格：￥1995.92

会员价格：￥1878.51

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Apolipoprotein C-III, human View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: MOLECULAR WEIGHT: 8,750 View All» Background Information: The physiological role of Apo CIII is unknown. It is suggested that Apo CIII may inhibit the activation of lipoprotein lipase by Apo CII. View All» Key Applications: Positive Control View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. View All» UniProt Summary: FUNCTION: SwissProt: P02656 # Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.SIZE: 99 amino acids; 10852 Da SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.PTM: O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues.DISEASE:SwissProt: P02656 # Defects in APOC3 may be a cause of hyperalphalipoproteinemia [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).SIMILARITY: SwissProt: P02656 ## Belongs to the apolipoprotein C3 family. View All» Species: Human View All» Brand Family: Chemicon View All» Source: Human plasma tested negative for HBsAg and HIV-I, HIV-II, HBc and Hepatitis C antibodies. All blood products should be treated as potentially infectious. View All» Presentation: Liquid in 10 mM NH4HCO3, pH 7.4. View All» UniProt Number: P02656 View All» Storage Conditions: Maintain at -20ºC or below in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. All blood products should be treated as potentially infectious. View All» Gene Symbol:

• APOC3

• ApoC-III

• Apo-CIII

• APOCIII

• MGC150353
  View All» Product Name: Apolipoprotein C-III, human View All» Entrez Gene Number: NM_000040.1 View All» Alternate Names: ApoCIII View All» Purity: > 95% by SDS-PAGE View All»
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