金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: GRK2 Long Name: G protein-coupled Receptor Kinase 2 Aliases: ADRBK1; BARK1; Beta-ARK1 Entrez Gene IDs: 156 (Human); 110355 (Mouse); 25238 (Rat) Background: GRKs (G Protein-coupled Receptor Kinases) G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.