R&D Systems代理MAB4408 Human TFF3 MAb (Clone 415921) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB4408 Human TFF3 MAb (Clone 415921) (100 UG)

2025-06-27

货号：MAB4408

品牌：R&D Systems

规格：100ug

目录价：￥4020.00

市场价格：￥3216.00

会员价格：￥3216.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TFF3 Long Name: Trefoil Factor 3 Aliases: ITF; TFI Entrez Gene IDs: 7033 (Human); 21786 (Mouse); 25563 (Rat) Background: TFF3

View TFF3 IHC images. TFF3 (Trefoil factor 3; also hP1.B and intestinal trefoil factor) is a 7 kDa member of the trefoil factor family of protease-resistant peptides. It is expressed by multiple epithelial cell types, acts in an autocrine or paracrine manner and contributes to epithelial cell migration and survival. TFF3 is secreted by mucus-producing goblet cells in the large and small intestines and lower respiratory tract.

Mature human TFF3 is 59 amino acids (aa) in length (aa 22 - 80). It contains one P (or trefoil) domain that is characterized by the presence of three cysteine bond-mediated loops (aa 30 - 72). Human TFF3 exists as both a monomer and disulfide-linked dimer. There are three potential isoform variants. One shows an alternate start site at Met8, a second shows a 50 aa N-terminal extension and a third shows a 109 aa substitution for aa 29 - 80. Over aa 21 - 80, human TFF3 shares 77%, 68% and 72% aa identity with mouse, canine, and rat TFF3, respectively.

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