金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: C5L2/GPR77 Long Name: C5a Anaphylatoxin Chemotactic Receptor C5L2 Aliases: GPR77 Entrez Gene IDs: 27202 (Human); 319430 (Mouse); 445269 (Rat) Background: C5L2 C5L2, also known as GPR77, is a 45 kDa 7TM receptor that binds the complement proteins C3a, C4a, and C5a as well as the acylation stimulating peptide (ASP). C5L2 is expressed on various hematopoietic cells where it promotes complement-mediated inflammation. ASP binding to C5L2 on adipocytes triggers triglyceride synthesis and glucose uptake and inhibits lipolysis.