R&D Systems代理MAB5010 Mouse IL-33 Propeptide MAb (Clone 518017) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB5010 Mouse IL-33 Propeptide MAb (Clone 518017) (100 UG)

2025-06-27

货号：MAB5010

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IL-33 Long Name: Interleukin 33 Aliases: C9orf26; DVS27; NF-HEV Entrez Gene IDs: 90865 (Human); 77125 (Mouse) Background: IL-33

View IL-33 IHC images. IL-33 is a proinflammatory protein that may also regulate gene transcription. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines and is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1alpha or IL-1 beta stimulation. Similar to IL-1, IL-33 can be cleaved in vitro by caspase-1, generating an N-terminal fragment that is slightly shorter than the C-terminal fragment. The N-terminal portion of full length IL-33 contains a predicted bipartite nuclear localization sequence and a homeodomain-like helix-turn-helix DNA binding domain.

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