金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: PLA2G1B Long Name: Phospholipase A2 Group IB Aliases: PLA2; PLA2A; PPLA2 Entrez Gene IDs: 5319 (Human); 18778 (Mouse); 29526 (Rat) Background: Phospholipase A2 Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction.