R&D Systems代理MAB59691 Human Cytosolic beta-Glucosidase/GBA3 MAb (Clone 728702) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB59691 Human Cytosolic beta-Glucosidase/GBA3 MAb (Clone 728702) (100 UG)

2025-06-28

货号：MAB59691

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Cytosolic beta-Glucosidase/GBA3 Aliases: CBGL1; GBA3; GLUC; KLrP Entrez Gene IDs: 57733 (Human); 289687 (Rat) Background: Cytosolic beta-Glucosidase

View GBA3 IHC images. There are three beta-glucosidases (GBA) in human genome. GBA1 endodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glucosylceramide. GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides. GBA3 is a cytosolic beta-glucosidase and is predominantly expressed in liver. GBA3 efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiological beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity, suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism. At the protein level, GBA3 shows significant homology (>40%) with Klotho protein that is known for its association with aging process.

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