金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FGL2 Long Name: Fibrinogen-like 2 Aliases: Fibroleukin; T49 Entrez Gene IDs: 10875 (Human); 14190 (Mouse); 84586 (Rat) Background: FGL2 FGL2 (fibrinogen-like protein 2), also called fibroleukin, is a 64-70 kDa secreted glycoprotein of the Fibrinogen-like superfamily. In the presence of acidic phospholipids and calcium, FGL2 has prothrombinase activity and acts as a procoagulant. In soluble form, FGL2 promotes T regulatory (Treg) activity and suppresses DC, T, and B cell immune reactivity, acting as an immune suppressor. A 260-280 aa FGL2 complex is thought to be a homotetramer.