R&D Systems代理MAB6028 Human TTK MAb (Clone 689913) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB6028 Human TTK MAb (Clone 689913) (100 UG)

2025-06-28

货号：MAB6028

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TTK Long Name: TTK Protein Kinase Aliases: MPS1L1; PYT Entrez Gene IDs: 7272 (Human); 22137 (Mouse); 315852 (Rat) Background: TTK

View TTK IHC images. TTK (Dual specificity Thr/Tyr kinase; also PYT and hMps1) is a 97-105 kDa member of the Ser/Thr protein kinase family of enzymes. It is expressed in rapidly proliferating tissues and cell lines, and participates in cell cycle regulation. In particular, it directs chromosome alignment, centrosome duplication, and spindle assembly checkpoint formation. Via phosphorylation, TTK is known to regulate p53, CDCA8 and TACC2. Human TTK is 857 amino acids (aa) in length and contains one protein kinase domain (aa 525-791). Activation occurs following homodimerization and autophosphorylation on Thr675, Thr676 and Thr686.

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