金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SALL4 Long Name: Sal-like 4 Aliases: DRRS; HSAL4; ZNF797 Entrez Gene IDs: 57167 (Human); 99377 (Mouse) Background: SALL4 SALL4 (SAL-like protein 4) is a member of the SAL protein family that possess multiple C2H2-type zinc-fingers. It is a transcriptional repressor when associated with histone deacetylase and a transcriptional activator of the Wnt pathway in its native form. It contributes to generation of induced pluripotent stem cells and to axis formation during development. It is frequently overexpressed in germ cell tumors and acute myeloid leukemias. Mutations of human SALL4 can result in conditions such as Okihiro, Duane Radial Ray, or Holt-Oram syndromes.