金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TORC2 Long Name: Transducer of Regulated CREB protein 1 Aliases: CRTC2 Entrez Gene IDs: 200186 (Human); 74343 (Mouse); 310615 (Rat) Background: TORC2 TORC2, also known as CREB-regulated transcription coactivator 2 (CRTC2), is an approximately 75 kDa protein that functions as a coactivator for CREB1 in promoting transcription through both consensus and variant cAMP response element (CRE) sites. TORC2 activity is important in regulating the expression of genes involved in cellular energy metabolism. Its O-glycosylation triggers TORC2-dependent induction of hepatic gluconeogenic enzymes. It mediates hypothalamic glucose sensing and also the sensing of endoplasmic reticulum stress. In addition, TORC2 contributes to the transcription of HTLV-1 genes and the activation of latent EBV infections.