金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: RLK/TXK Long Name: Resting Lymphocyte Kinase Aliases: BTKL; PSCTK5; PTK4; TXK Entrez Gene IDs: 7294 (Human) Background: RLK RLK (resting lymphocyte kinase), also called TXK (T cell-expressed kinase) or PTK4, is a protein tyrosine kinase of the TEK family. It is expressed in T cells and some myeloid cells, especially in Th1 cells in inflammatory diseases such as rheumatoid arthritis and Behcet’s disease. Upon TCR stimulation, it translocates to the nucleus and induces IFN gamma production. An alternate start site creates two forms, a resident nuclear 55 kDa form and a larger (~58 kDa) cytoplasmic or plasma membrane-associated form.