金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: PAK2 Long Name: p21-activated Kinase 2 Aliases: gamma-PAK; PAK65; S6/H4 Kinase Entrez Gene IDs: 5062 (Human); 224105 (Mouse); 29432 (Rat) Background: PAK Family PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).