金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: NIK/MAP3K14 Long Name: NF-kappa-beta Inducing Kinase Aliases: FTDCR1B; HSNIK; MAP3K14 Entrez Gene IDs: 9020 (Human); 53859 (Mouse); 360640 (Rat) Background: NIK NIK (nuclear factor inducing kinase), also called MAP3K14 or MAP4K4, is a widely expressed 947 amino acid (aa), approximately 100 kDa cytoplasmic protein of the MAP kinase family. NIK participates in a non-canonical NFkappaB signaling cascade in which its activity and expression are elevated by TNF and related ligands. NIK activates IKK alpha/beta, which releases NFkappaB subunits for translocation to the nucleus.