R&D Systems代理MAB72891 Human Mind Bomb 2/MIB2 MAb (Clone 739505) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB72891 Human Mind Bomb 2/MIB2 MAb (Clone 739505) (100 UG)

2025-06-27

货号：MAB72891

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Mind Bomb 2/MIB2 Long Name: Mindbomb Homolog 2 Aliases: MIB2; Mind Bomb-2; Novelzin; SKD; Skeletrophin; ZZANK1; ZZZ5 Entrez Gene IDs: 142678 (Human); 76580 (Mouse) Background: Mind Bomb 2

View Mind Bomb 2 IHC images. Mind Bomb 2/MIB2, also called skeletrophin, is a widely expressed, 1013 amino acid cytoplasmic phosphoprotein that is an E3 ubiquitin ligase for Notch ligands such as Jagged-2. It contains two MIB/HERC2 domains surrounding a ZZ-type zinc finger, an ankyrin repeat domain, and two RING-type zinc fingers that have E3 ubiquitin ligase activity. MIB-2 has been detected as a 70 kDa form in skeletal muscle, binds actin, and is downregulated in malignant melanoma.

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