金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: PTPRU Long Name: Protein Tyrosine Phosphatase Receptor-type U Aliases: FMI; GLEPP1; PCP-2; pi R-PTP-Psi; PTP-J; PTP-PI; PTPRO; R-PTP-U Entrez Gene IDs: 10076 (Human); 19273 (Mouse); 116680 (Rat) Background: PTPRU Protein Tyrosine Phosphatase, receptor type U (PTPRU), also called PCP-2 or PTPpi, is a type IIb receptor-like protein tyrosine phosphatase (PTPR). The extracellular domain contains MAM, Ig-like C-type and Fibronectin III domains that often mediate cell adhesion, but unlike other family members, PTPRU does not appear to mediate homophilic cell aggregation. It does, however, antagonize Wnt signaling in adherens junctions by inhibiting beta-catenin-mediated gene transcription.