金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: ZAP70 Long Name: Zeta-chain [TCR] Associated Protein Kinase 70 kDa Aliases: mrtle; mur; SRK; STD; TZK Entrez Gene IDs: 7535 (Human); 22637 (Mouse); 301348 (Rat) Background: ZAP70 View ZAP70 IHC images. ZAP70 is a cytoplasmic tyrosine kinase that is essential for TCR signal transduction. It is expressed in T and NK cells, associates with the TCR zeta chain, and is phosphorylated upon TCR stimulation. This activates ZAP70, which subsequently interacts with several Sh2 or PTB-containing adaptors and enzymes such as Vav, Shc Abl and Lck.