R&D Systems代理PP-K9218-00 Human HNF-4 alpha/NR2A1 MAb (Clone K9218) (100 UG)-试剂-金山科研平台

R&D Systems代理PP-K9218-00 Human HNF-4 alpha/NR2A1 MAb (Clone K9218) (100 UG)

2025-06-27

货号：PP-K9218-00

品牌：R&D Systems

规格：100ug

目录价：￥5620.00

市场价格：￥4496.00

会员价格：￥4496.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: HNF-4 alpha/NR2A1 Long Name: Hepatocyte Nuclear Factor-4, alpha Aliases: HNF4A; MODY1; NR2A1; TCF14 Entrez Gene IDs: 3172 (Human) Background: HNF-4 alpha

View HNF-4 alpha IHC images.Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha; NR2A1) is a member of the orphan nuclear receptor family. HNF4 alpha is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4 alpha in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4 alpha gene is alternatively spliced and may generate up to nine different isoforms, HNF4 alpha 1 through HNF4 alpha 9. The expression of HNF-4 gamma (NR2A2) is observed in the pancreas, kidney, small intestine, and testes with no expression detected in the liver. The level of HNF-4 gamma is less 10% than that of HNF-4 alpha.

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