金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: 5-Lipoxygenase Aliases: 5LPG; ALOX5; LOG5; LOX5A Entrez Gene IDs: 240 (Human); 11689 (Mouse); 25290 (Rat) Background: 5-Lipoxygenase 5-Lipoxygenase (5-LO) is a nonheme iron dioxygenase that converts nuclear membrane arachidonic acid into leukotriene A4 (LTA4). 5-LO is found in leukocytes and generally exists in the cytoplasm but may translocate into the nucleus when activated. In the nucleus, its enzyme products impact gene expression; in the cytosol, its products are secreted and contribute to inflammation.